Calming the Skin — Not Just Moisturizing

Eczema is not simply dry skin — it is inflamed skin. Controlling inflammation is essential to reduce itching, prevent flares, and allow the barrier to heal.

Two helpful over-the-counter ingredients are niacinamide and 18β-glycyrrhetinic acid.

18β-Glycyrrhetinic Acid (Licorice Root Extract)

This plant-derived anti-inflammatory works similarly to a very mild topical steroid, but without steroid side-effects.

Benefits

• Reduces redness and irritation
• Calms itching
• Helps suppress inflammatory signals in eczema skin
• Supports barrier recovery

Because it soothes without thinning the skin, it is useful for sensitive areas and long-term maintenance care.

Why Niacinamide Helps

Niacinamide (vitamin B3) supports the skin on multiple levels:

• Decreases redness and inflammation
• Increases ceramide production
• Strengthens the skin barrier
• Reduces water loss (TEWL)
• Supports cellular repair processes

Clinical studies show 4–5% niacinamide can improve hydration, redness, and eczema severity within about 4–8 weeks. It is also beneficial for acne and rosacea-prone skin.

The Bottom Line

Niacinamide repairs and strengthens the barrier, while 18β-glycyrrhetinic acid calms inflammation and itching.
Together, they provide safe, steroid-sparing support for eczema-prone skin and fit well into long-term barrier-focused care.